L-lLysyl-L-glutaminyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl--L-lysine

产品名称：

1507930-57-5
Gap19 trifluoroacetate salt
KQIEIKKFK trifluoroacetate salt
Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Ly trifluoroacetate salt
L-lLysyl-L-glutaminyl-L-isoleucyl-L-α-glutamyl-L-isoleucyl-L-lysyl-L-lysyl-L-phenylalanyl--L-lysine

产品介绍：

产品说明

应用

Gap19 trifluoroacetate salt has been used to inhibit Ca²⁺/calmodulin (CaM) gating response of connexin 43 (Cx43) gap junctions.

包装

1 mg in glass bottle

生化/生理作用

Gap19, nonapeptide from the cytoplasmic loop of Connexin-43, is a selective blocker of connexin 43 (Cx43) hemichannel that does not block GJ or Cx40/Panx-1 channels in cardiomyocytes and astrocytes. Gap19 prevents Cx43 hemichannel opening and protect against myocardial ischemia/reperfusion injury.

基本信息

经验(实验)分子式	C₅₅H₉₆N₁₄O₁₃ · xC₂HF₃O₂
分子量	1161.44 (free base basis)
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to off-white
运输	wet ice
储存温度	−20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable