MMK-1 trifluoroacetate

产品名称：

271246-66-3
MMK-1 trifluoroacetate
L-Methionine, L-leucyl-L--glutamyl-L-seryl-L-isoleucyl-L-phenylalanyl-L-arginyl-L-seryl-L-leucyl-L-leucyl-L-phenylalanyl-L-arginyl-L-valyl-
LESIFRSLLFRVM trifluoroacetate
GTPL6240
MMK-1 TFA
Leu-Glu-Ser-Ile-Phe-Arg-Ser-Leu-Leu-Phe-Arg-Val-Met trifluoroacetate

产品介绍：

产品说明

生化/生理作用

MMK-1 is a potent and selective FPR2 (FPRL-1) agonist (Ca²⁺ flux EC50 <2 nM/FPR2 vs. >10 μM/FPR1 with respective HEK293 transfectants) and an effective calcium-mobilizing and chemotactic agent for human monocytes & neutrophils (1-1000 nM). MMK-1 increases pertussis toxin-sensitive inflammatory cytokines production in human monocyte cultures (50 ng/mL PT & 10 μM MMK-1), exerts anxiolytic-like activities in mice (100 pmol/mouse icv) and shows anti-alopecia efficacy in rats in vivo (100 mg/kg p.o. or 10 mg/kg i.p.).

基本信息

经验(实验)分子式	C₇₅H₁₂₃N₁₉O₁₈S · xC₂HF₃O₂
分子量	1610.96 (free base basis)

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	film or powder
颜色	white to beige
储存温度	−20℃