N-C12-desoxymethylsphinganine

产品名称：

1246298-41-8
N-C12-desoxymethylsphinganine
N-dodecanoyl-1-desoxymethylsphinganine (m17:0/12:0); N-C12-1-desoxyMeDHCer; 110959

产品介绍：

产品说明

一般描述

N-C12-desoxymethylsphinganine commonly referred to as 1-deoxydihydroceramide (1-deoxyDHCer), is the N-acylated form of 1-deoxysphinganine, a potent inhibitor of sphingolipid metabolism.
Commonly referred to as 1-desoxymethyldihydroceramide (1-desoxyMeDHCer), this product is the N-acylated form of 1-desoxymethylsphinganine, a potent inhibitor of sphingolipid metabolism. The biological activity of 1-desoxyMeDHCer is not clearly understood at this time.

生化/生理作用

Ceramide synthases (CerS) catalyzes the acylation of sphingoid bases using fatty acyl-CoA and its inhibition results in decrease of desoxymethylsphinganine (N-acylsphinganines (dihydroceramides)) levels and accumulation of sphinganine (Sa). Dihydroceramides (DHCer) are intermediates of ceramide biosynthesis.

包装

5 mL Amber Glass Screw Cap Vial (860461P-1mg)

基本信息

经验(实验)分子式	C₂₉H₅₉NO₂
分子量	453.78

产品性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (860461P-1mg)
manufacturer/tradename	Avanti Polar Lipids 860461P
运输	dry ice
储存温度	−20℃

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3