Nitric Oxide Synthase Inhibitor Screening Kit

产品说明

一般描述

Nitric oxide (NO) is a reactive radical that plays an important role in many key physiological functions. NO is the oxidation product of arginine by nitric oxide synthase (NOS) and is involved in host defense development, activation of regulatory proteins and direct covalent interaction with functional biomolecules. Inhibition of NOS has the potential to produce diverse biological effects, particularly in the cardiovascular system. Simple, direct and non-radioactive procedures for measuring NOS are becoming popular in research and drug discovery.

特点和优势

Compatible with high-throughput handling systems.

适用性

Suitable for inhibitor screening and evaluation of nitric oxide synthase inhibitors.

原理

The Nitric Oxide Synthase Inhibitor Screening Kit involves two steps: a NOS reaction step during which NO is produced followed by an NO detection step. Since the NO generated by NOS is rapidly oxidized to nitrite and nitrate, the NO production is measured following reduction of nitrate to nitrite using an improved Griess method.

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H290 - H302 - H315 - H319
预防措施声明	P234 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3