Phospho-Stat3 (pTyr⁷⁰⁵) and pan-Stat3 ELISA Kit

产品说明

一般描述

The Phospho-Stat3 (pTyr⁷⁰⁵) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.

免疫原

Stat3 (pTyr⁷⁰⁵) synthetic phosphopeptide, Recombinant Human Stat3

应用

Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H290 - H335
危险分类	Met. Corr. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	8B - Non-combustible, corrosive hazardous materials