产品说明
一般描述
Sphingosine-1-phosphate (S1P) or D-erythro-sphingosine-d7-1-phosphate, is a deuterated sphingolipid. S1P, a zwitterionic sphingolipid, is an important cellular metabolite and signaling lipid in animal cells. It has also been found in insects, yeasts and plants. S1P is synthesized from the sphingosine kinase (Sph) 1 and SphK2 present in cytosol and nucleus, respectively.
应用
Sphingosine-1-phosphate (S1P)-d7 has been used as a standard in ultra-high performance liquid chromatography (UHPLC)-Q exactive for validation and quantitative analyses of S1P.
生化/生理作用
Sphingosine-1-phosphate (S1P) plays a vital role in mammalian brain and cardiac development. It is essential for maturation of the systemic circulatory system and lymph vessels. Additionally, S1P is implicated in trafficking and effector functions of lymphocytes and other blood stem cells. It also provides protection against various forms of tissue injury. S1P also acts as a tumor promoting lipid. S1P has an ability to enhance erythrocyte glycolysis and oxygen delivery therefore, it can be used to treat tissue hypoxia.
包装
5 mL Amber Glass Screw Cap Vial (860659P-1mg)
基本信息
| 经验(实验)分子式 | C18H31D7NO5P |
| 分子量 | 386.51 |
| NACRES | NA.25 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (860659P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 860659P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | [H][C@@]([C@]([NH3+])([H])COP([O-])(O)=O)(O)/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H] |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| 闪点(F) | No data available |
| 闪点(C) | No data available |
Sigma-Aldrich
m.cnreagent.com
