产品说明
一般描述
Trihydroxycholestanoic acid (THCA) is an oxidative metabolite of cholesterol and a precursor to bile acids. Very long-chain acyl-CoA synthetase (VLCS) associated with endoplasmic reticulum and peroxisomes activates THCA, the C27 bile acid intermediate.
应用
Trihydroxycholestanoic acid has been used as a sterol to test its reactivity with human mincle protein.
生化/生理作用
Trihydroxycholestanoic acid (THCA) and dihydroxycholestanoic (DHCA) accumulation is observed in Zellweger syndrome and cholestatic liver disease. The synthesis of (25R)-isomer of DHCA and THCA is favored by mitochondrial 27-hydroxylase.
包装
5 mL Amber Glass Screw Cap Vial (700070P-1mg)
基本信息
| 经验(实验)分子式 | C27H46O5 |
| 分子量 | 450.65 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 1 mg (700070P-1mg) |
| manufacturer/tradename | Avanti Polar Lipids 700070P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| InChI | 1S/C27H46O5/c1-15(6-5-7-16(2)25(31)32)19-8-9-20-24-21(14-23(30)27(19,20)4)26(3)11-10-18(28)12-17(26)13-22(24)29/h15-24,28-30H,5-14H2,1-4H3,(H,31,32)/t15-,16?,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1 |
| InChI key | CNWPIIOQKZNXBB-VCVMUKOKSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | No data available |
| 闪点(C) | No data available |
Sigma-Aldrich
m.cnreagent.com
