Anti-Human IgM (Fc5μ) -Rhodamine antibody produced in rabbit

产品说明

一般描述

There are five immunoglobulin classes in humans. Out of these, immunoglobulin M (IgM ) is a high molecular weight protein that has five or six subunits. IgM monomers are made of two heavy chains and two light chains connected by a disulfide bond. Human serum shows low concentration of IgM monomers. It has a high carbohydrate content of about 12%. It is the first immunoglobulin produced by neonates.

特异性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Human IgM coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Rabbit Serum, Human IgM and Human Serum. Specificity was confirmed by ELISA at less than 1% cross reactivity against other Human heavy or light chain isotypes.

免疫原

Human IgM Fc5μ fragment

生化/生理作用

Immunoglobulin M (IgM) acts as an antigen specific part of the B cell antigen receptor on the surface of B lymphocytes that are not stimulated, in its monomeric form. Polymeric IgM molecules also serve as important activators of the classical complement cascade. IgM is essential in agglutination and cytolytic reactions.

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重悬

Reconstitute with 1.0 mL deionized water (or equivalent).

基本信息

产品性质

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H311 - H411
预防措施声明	P280 - P301 + P312 + P330 - P302 + P352 + P312
危险分类	Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2
补充剂危害	EUH032
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable