β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt

产品名称：

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt
β-NADPH
Coenzyme II reduced tetrasodium salt
Triphosphopyridine nucleotide reduced tetrasodium salt
NADPH Na₄
2′-NADPH
TPNH₂ Na₄
Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt
β-烟酰胺腺嘌呤二核苷酸 2′-还原磷酸盐四钠盐
磷酸二氢烟酰胺腺嘌呤二核苷酸四钠盐
还原型三磷酸吡啶核苷酸四钠盐
NADPH Na ₄
辅酶 II减少四钠盐

产品介绍：

产品说明

应用

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP⁺/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay.

生化/生理作用

β-烟酰胺腺嘌呤二核苷酸 2′-磷酸盐 (NADP ⁺) 和 β-烟酰胺腺嘌呤二核苷酸 2′-还原磷酸盐 (NADPH) 包含辅酶氧化还原对 (NADP ⁺：NADPH)，参与广泛的酶催化氧化还原反应。NADP ⁺/NADPH 氧化还原对促进合成代谢反应中的电子转移，如脂质和胆固醇生物合成和脂肪酰基链的延长。NADP ⁺/NADPH 氧化还原对被用于多种抗氧化机制，在该机制中可防止活性氧化物质积聚。NADPH 在体内通过磷酸戊糖途径 (PPP) 生成。

制备说明

化学还原

其他说明

根据 UV-Vis 测定的 NADPH 含量包装。

基本信息

经验(实验)分子式	C₂₁H₂₆N₇Na₄O₁₇P₃
分子量	833.35
EC 号	214-664-6
MDL编号	MFCD00036263
PubChem化学物质编号	24897841
NACRES	NA.51

产品性质

质量水平	200
测定	~95%
形式	powder
包装	vial of 10 mg
InChI	1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
InChI key	WYWWVJHQDVCHKF-MPUNMZHWSA-J