2-氟-5-硝基苯甲酸

产品名称：

7304-32-7
2-Fluoro-5-nitrobenzoic Acid
2-氟-5-硝基苯甲酸

产品介绍：

产品说明

一般描述

2-Fluoro-5-nitrobenzoic acid is reported to react with an aldehyde, isonitrile and a primary amine tethered to a Boc-protected internal amino or hydroxyl nucleophile, to afford the Ugi product.

应用

2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of:

dibenz[b,f]oxazepin-11(10H)-ones, via the nucleophilic aromatic substitution (S_NAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support
synthesis of substituted dibenzazocines on solid support, via S_NAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols
in the synthesis of oxazepines

包装

5 g in glass bottle

基本信息

线性分子式	FC₆H₃(NO₂)CO₂H
分子量	185.11
MDL编号	MFCD00134238
PubChem化学物质编号	24862326
NACRES	NA.22

产品性质

质量水平	100
测定	98%
mp	142-144 ℃ (lit.)
SMILES string	OC(=O)c1cc(ccc1F)[N+]([O-])=O
InChI	1S/C7H4FNO4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3H,(H,10,11)
InChI key	ICXSHFWYCHJILC-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves