BocNH-PEG4-acid

产品名称：

876345-13-0
BocNH-PEG4-acid
Boc-NH-PEG4-CH₂COOH
2,2-Dimethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azanonadecan-19-oic acid

产品介绍：

产品说明

应用

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG4-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation

其他说明

A Hexylchloride-Based Catch-and-Release System for Chemical Proteomic Applications

A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₁₅H₂₉NO₈
分子量	351.39

产品性质

形式	liquid
reaction suitability	reaction type: Pegylations reagent type: cross-linking reagent
折射率	n/D 1.4641
密度	1.1395 g/mL
储存温度	−20℃
SMILES string	OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O OC(COCCOCCOCCOCCNC(OC(C)(C)C)=O)=O

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable