产品说明
应用
Fmoc-N-Me-Cys(Trt)-OH is a Fmoc-protected derivative of N-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. The residue attached to the amino group of N-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. The introduction of this Fmoc-protected derivative is best achieved using HATU as a coupling reagent in the presence of DIPEA (N, N-Diisopropylethylamine).
It can also be used to prepare Fmoc-N-Me-Cys(Trt)-OAllyl intermediate for the solid-phase synthesis of dithiol Triostin A.
包装
1 g in glass bottle
基本信息
| 经验(实验)分子式 | C38H33NO4S |
| 分子量 | 599.74 |
| NACRES | NA.26 |
产品性质
| 质量水平 | 100 |
| 测定 | 97% (HPLC) |
| 形式 | powder or crystals |
| 旋光性 | [α]22/D -25.0°, c = 0.5% in dichloromethane |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| mp | 234-239 ℃ |
| application(s) | peptide synthesis |
| 官能团 | Fmoc |
| 储存温度 | 2-8℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
