产品说明
应用
硬脂酸镁已被用作片剂和胶囊润滑剂。也用于制备微囊。
生化/生理作用
硬脂酸镁是硬脂酸的镁盐，具有润滑性能，因此在将化学粉末压制成固体片剂时可防止成分粘在制造设备上。用硬脂酸镁干包衣可改善流动性、改善流动性和润滑效果、可压片性以及不受抑制的溶出度。
基本信息
| 线性分子式 | [CH3(CH2)16CO2]2Mg |
| 分子量 | 591.24 |
| Beilstein | 3919702 |
| EC 号 | 209-150-3 |
| MDL编号 | MFCD00036391 |
| PubChem化学物质编号 | 57648176 |
| NACRES | NA.22 |
产品性质
| 等级 | puriss. |
| 测定 | ≥40% stearic acid basis (GC) ≥90% stearic and palmitic acid basis 4.0-5.0% Mg basis (calc on dry sub.) |
| 质量 | meets analytical specification of Ph. Eur., BP |
| 杂质 | acidity or alkalinity, complies microbiological impurity, in accordance residual solvents, complies |
| 缺失 | ≤6.0% loss on drying, 105 ℃ |
| mp | 200 ℃ (lit.) |
| 酸值 | 195‑210(fatty acid) |
| 溶解性 | alcohol: insoluble diethyl ether: insoluble water: insoluble |
| 痕量阴离子 | chloride (Cl-): ≤1000 mg/kg sulfate (SO42-): ≤5000 mg/kg |
| 痕量阳离子 | Cd: ≤3 mg/kg Ni: ≤5 mg/kg Pb: ≤10 mg/kg |
| 适用性 | in accordance for fatty acid composition passes test for identity |
| application(s) | pharmaceutical (small molecule) |
| SMILES string | CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC |
| InChI | 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2 |
| InChI key | HQKMJHAJHXVSDF-UHFFFAOYSA-L |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
