产品说明
应用
Poloxamers are nonionic, triblock copolymers containg a central hydrophobic chain of poly(propylene glycol) (PPG) and two terminal hydrophilic chains of poly(ethylene glycol) (PEG). Due to their amphiphilic structure, poloxamer solutions feature temperature dependent self-assembling and thermo-gelling behavior. Concentrated aqueous solutions of poloxamers are liquid at low temperature and form a gel at higher temperature, in a reversible process. This characteristic has allowed for these materials to be used as drug carriers for most routes of administration including oral, topical, intranasal, ocular, and parenteral. Methacrylate-modified derivatives are most commonly used as thermosensitive hydrogels for drug delivery and 3D bioprinting applications. After casting or printing, the material can be crosslinked to preserve the hydrogel structure.
基本信息
线性分子式 | C4H5O[C2H4O]x[C3H6O]y[C2H4O]zC4H5O2 |
产品性质
形式 | powder |
质量水平 | 100 |
分子量 | average Mn ~14,600 |
包含 | ≤1500 ppm MeHQ |
颜色 | off-white to yellow |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich