产品说明
应用
This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG6-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.
法律信息
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
基本信息
| 经验(实验)分子式 | C16H28O8 |
| 分子量 | 348.39 |
| MDL编号 | MFCD28950778 |
| NACRES | NA.22 |
产品性质
| 测定 | ≥95% |
| 形式 | liquid |
| reaction suitability | reaction type: click chemistry reagent type: cross-linking reagent |
| 折射率 | n |
| 储存温度 | −20℃ |
| SMILES string | OC(CCOCCOCCOCCOCCOCCOCC#C)=O OC(CCOCCOCCOCCOCCOCCOCC#C)=O |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
