产品说明

应用

2,4-Dichloro-5-fluoropyrimidine can be used as a starting material to synthesize:

• 5-fluoropyrimidine-2-carboxamides and 5-fluoropyrimidine-4-carboxamides as potential kinase inhibitors.
• A series of 2,4-diamino-5-fluoropyrimidine derivatives as potential protein kinase Cθ inhibitors.
• 2,4-Bisanilinopyrimidine derivatives as potential aurora kinases inhibitors.
• 5-fluoro-N,N-bis(4-methoxyphenyl)-2,4-pyrimidinediamine by reacting with p-methoxy aniline in the presence of DIPEA.
• 2-chloro-5-fluoro-4-(4-fluorophenyl)pyrimidine by Suzuki coupling reaction in the presence of (4-fluorophenyl)boronic acid triphenylphosphine, and palladium(II) acetate catalyst.
• 5-fluoro-2-(piperidin-4-yloxy)pyrimidin-4-amine, a scaffold, which is used in the preparation of potent deoxycytidine kinase inhibitors.

包装

1 g in glass bottle

基本信息

产品性质

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H314
预防措施声明	P260 - P280 - P301 + P312 + P330 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Skin Corr. 1B
储存分类代码	8A - Combustible, corrosive hazardous materials
WGK	WGK 3
闪点(F)	222.8 °F - closed cup
闪点(C)	106 ℃ - closed cup
个人防护装备	Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges