Anti-Connexin-26 Antibody, clone 3B12.1

产品说明

一般描述

Connexin-2 is also known as Connexin Gap junction beta-2 protein (GJB2) and Connexin-26 (Cx26). The connexins are transmembrane channels that diffuse low MW materials from one cell to a neighboring cell. Aberrant connexin-2 can cause deafness autosomal recessive type 1A (DFNB1A), deafness autosomal dominant type 3A (DFNA3A), Vohwinkel syndrome (VS), palmoplantar keratoderma with deafness (PPKDFN), keratitis-ichthyosis-deafness syndrome (KID syndrome), Bart-Pumphrey syndrome (BPS), and ichthyosis hystrix-like with deafness syndrome (HID syndrome).

特异性

Other homologies: Mouse (92% sequence homology).

免疫原

KLH-conjugated linear peptide corresponding to human Connexin-26.

应用

Research Category
Cell Structure
Anti-Connexin-26 Antibody, clone 3B12.1 is a highly specific mouse monoclonal antibody, that targets CX26 & has been tested in western blotting & IHC.
Research Sub Category
Adhesion (CAMs)
Immunohistochemistry Analysis: A 1:4,000-8,000 dilution from a representative lot detected Connexin-26 in human colon and human liver tissue.

质量

Evaluated by Western Blotting in rat liver tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Connexin-26 in 10 µg of rat liver tissue lysate.

目标描述

~26 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat liver tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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