BocNH-PEG5-acid

产品名称：

890152-41-7
BocNH-PEG5-acid
2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid
Boc-NH-PEG5-CH₂COOH

产品介绍：

产品说明

应用

This heterobifunctional, PEGylated crosslinker features a carboxylic acid at one end and Boc-protected amino group at the other, which can be deprotected with mildly acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. BocNH-PEG5-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation.

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式	C₁₇H₃₃NO₉
分子量	395.45

产品性质

形式	liquid
reaction suitability	reaction type: Pegylations reagent type: cross-linking reagent
储存温度	−20℃
SMILES string	OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O OC(COCCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable