1,8-二羟基-3-（羟甲基）蒽甲苯

产品名称：

481-72-1
Diacerein impurity B
1,8-Dihydroxy 3-hydroxymethylanthraquinone
Rhabarberone
1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone
Aloe-emodin
3-Hydroxymethylchrysazine
芦荟大黄素
1,8-二羟基-3-（羟甲基）蒽甲苯
3-羟甲基白杨嗪
弹力素
1,8-二羟基3-羟甲基蒽甲苯

产品介绍：

产品说明

一般描述

Diacerein is known to be a suitable drug to treat osteoarthritis and prevent vascular diseases. It is a semi-synthetic anthraquinone derivative which acts by inhibiting the production of interleukin-1 and secretion of metalloproteases.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

复方泻药/泻药；通过释放内源性乙酰胆碱来增加肠道平滑肌的收缩。抗肿瘤活性与活性氧簇 (ROS) 产生增加相关，活性氧簇反过来降低线粒体跨膜电位，从而诱导渗透性转换，启动一系列事件，最终导致细胞凋亡。遗传毒性和致突变性似乎是由于芦荟大黄素抑制了拓扑异构酶II的活性。

包装

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₅H₁₀O₅
分子量	270.24
Beilstein	2059062
MDL编号	MFCD00017373
PubChem化学物质编号	329831502
NACRES	NA.24

产品性质

生物来源	synthetic
等级	pharmaceutical primary standard
agency	EP
形式	solid
manufacturer/tradename	EDQM
technique(s)	gas chromatography (GC): suitable liquid chromatography (LC): suitable
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
InChI	1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
InChI key	YDQWDHRMZQUTBA-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P301 + P312 + P330
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable