4′-去甲基表鬼臼毒素 -(4,6-O-亚乙基-β-<SC>D</SC>-吡喃葡萄糖苷)

产品名称：

33419-42-0
Etoposide
VP-16-213
4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside)
依托泊苷
4′-去甲基表鬼臼毒素 -(4,6-O-亚乙基-β-D-吡喃葡萄糖苷)

产品介绍：

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

依托泊甙是一种抗肿瘤试剂，和拓扑异构酶II和DNA结合，增强DNA双链和单链剪切和可逆抑制解除。在S期和G2期阻止细胞周期；诱导正常和肿瘤细胞系凋亡；抑制癌蛋白Mdm2的合成，引起Mdm2过量表达的肿瘤系细胞凋亡。

包装

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₂₉H₃₂O₁₃
分子量	588.56
MDL编号	MFCD00869325
PubChem化学物质编号	329799033
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26
InChI	1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
InChI key	VJJPUSNTGOMMGY-MRVIYFEKSA-N
Gene Information	human ... TOP2A(7153), TOP2B(7155)

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H350 - H361d - H412
预防措施声明	P201 - P280 - P301 + P312 + P330 - P308 + P313
危险分类	Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Repr. 2
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable