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Hydroxy-PEG6-t-butyl ester

品牌
Sigma-Aldrich
CAS
361189-64-2
货号
902578
包装型号
规格纯度
≥95%
参考价格
1375.45 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
361189-64-2
Hydroxy-PEG6-t-butyl ester
tert-Butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate
HO-PEG6-CO-OtBu
产品介绍:

产品说明

应用

This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or roteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation.

其他说明

Synthesis and Molecular Recognition Studies of the HNK-1 Trisaccharide and Related Oligosaccharides. The Specificity of Monoclonal Anti-HNK-1 Antibodies as Assessed by Surface Plasmon Resonance and STD NMR

Maleimide-oligo(ethylene glycol) Derivatives of Camptothecin as Albumin-Binding Prodrugs: Synthesis and Antitumor Efficacy

法律信息

PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

基本信息

经验(实验)分子式C19H38O9
分子量410.50

产品性质

测定≥95%
形式liquid
reaction suitabilityreagent type: cross-linking reagent
折射率n/D 1.454
密度1.068
储存温度−20℃
SMILES stringO=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCO

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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