产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
针对结核菌的抗生素,抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性,在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。
包装
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
经验(实验)分子式 | C6H7N3O |
分子量 | 137.14 |
Beilstein | 119374 |
MDL编号 | MFCD00006426 |
PubChem化学物质编号 | 329815311 |
NACRES | NA.24 |
产品性质
等级 | pharmaceutical primary standard |
agency | EP Reference Standard |
manufacturer/tradename | EDQM |
mp | 171-173 ℃ (lit.) |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
储存温度 | 2-8℃ |
SMILES string | NNC(=O)c1ccncc1 |
InChI | 1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10) |
InChI key | QRXWMOHMRWLFEY-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 |
预防措施声明 | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313 |
危险分类 | Acute Tox. 4 Oral - Skin Irrit. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich