产品说明
应用
Molsidomine has been used as nitric oxide (NO)-releasing vasodilator to study the effect of NO on angiostatin production in aging rat kidneys.
包装
500 mg in poly bottle
5 g in poly bottle
生化/生理作用
Molsidomine is an effective vasodilator and a long-lasting nitric oxide (NO) donor. It is a pro-drug that is enzymatically decarboxylated to form 3-morpholinosydnone imine (SIN-1) in the liver. Molsidomine is used as an anti-anginal agent and possesses antioxidant properties. It may be used to treat cisplatin-induced oxidative stress in the liver tissue. Molsidomine has also been used during angina pectoris, heart failure, and after myocardial infarction.
Orally active, long acting vasodilator; antianginal; converted by the liver to the active metabolite, SIN-1
基本信息
| 经验(实验)分子式 | C9H14N4O4 |
| 分子量 | 242.23 |
| EC 号 | 247-207-4 |
| MDL编号 | MFCD00869301 |
| PubChem化学物质编号 | 24278544 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 储存温度 | 2-8℃ |
| SMILES string | CCOC(=O)N=C1O[N-][N+](=C1)N2CCOCC2 |
| InChI | 1S/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3/b10-8- |
| InChI key | XLFWDASMENKTKL-NTMALXAHSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
