产品说明
一般描述
An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
Note: 1 set = 5 x 700 mg.
An organomercurial agent used for the activation of latent matrix metalloproteinases (MMPs) in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.
包装
700 mg in Plastic Bag(s)
1 set in Fibre case
生化/生理作用
Product does not compete with ATP.
Primary Target
Activation of latent MMPs in vitro
Reversible: no
Cell permeable: no
警告
Toxicity: Highly Toxic (H)
重悬
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.
其他说明
Chen, J.-M., et al. 1991. J. Biol. Chem. 266, 5113.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, G.P., et al. 1983. Biochemistry22, 61.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C8H9HgNO2 |
| 分子量 | 351.75 |
| MDL编号 | MFCD00007820 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥90% (titration) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze |
| 颜色 | yellow |
| 溶解性 | 0.1 M NaOH: 10 mg/mL DMSO: 10 mg/mL |
| 运输 | ambient |
| 储存温度 | 10-30℃ |
| InChI | 1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1 |
| InChI key | RXSUFCOOZSGWSW-UHFFFAOYSA-M |
安全信息
| 象形图 |    |
| 警示用语： | Danger |
| 危险声明 | H300 + H310 + H330 - H373 - H410 |
| 预防措施声明 | P262 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
| 危险分类 | Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 |
| 储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
