产品说明
生化/生理作用
Bisindolylmaleimides (BIM) comprises a group of 11 compounds from BIM-I to BIM-XI. BIMs act as an inhibitor of protein kinase C (PKC). They are derived from staurosporine. BIM IX due to its proapoptotic functionality could be useful in targeting tumor proliferation.
基本信息
| 经验(实验)分子式 | C20H13N3O2 |
| 分子量 | 327.34 |
| MDL编号 | MFCD00236432 |
| PubChem化学物质编号 | 24891709 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% (TLC) |
| 形式 | solid |
| 颜色 | dark red |
| 溶解性 | DMSO: soluble methanol: soluble |
| 储存温度 | −20℃ |
| SMILES string | O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c4c[nH]c5ccccc45 |
| InChI | 1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25) |
| InChI key | DQYBRTASHMYDJG-UHFFFAOYSA-N |
| Gene Information | human ... CDK2(1017), EGFR(1956) rat ... Prkca(24680) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
