2,3-二甲氧基-5-甲基-<I>对</I>苯醌

产品名称：

605-94-7
2,3-Dimethoxy-5-methyl-p-benzoquinone
Coenzyme Q₀
2,3-二甲氧基-5-甲基-对苯醌

产品介绍：

产品说明

一般描述

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q₀ or DMM) is present in all the cells including neural cells.

应用

Coenzyme Q0 inhibits (via radical quenching) reactions of gamma-irradiation induced homolytic cleavage of O-glycoside bonds in polysaccharides. Coenzyme Q0 induces apoptosis and modulates the cell cycle in estrogen receptor negative breast cancer cells. It is toxic to other cells such as insulin producing cells.
2,3-Dimethoxy-5-methyl-p-benzoquinone has been used:

as a tau protein fibrillization inducer to determine the regions of tau involved in the formation of paired helical filaments (PHFs)
as a component in buffer B for cytochrome oxidation assay with subsaturating light
in the RPMI-1640 medium for 2,3-bis-(2-methoxy-4-nitro-5-sulphenyl)-(2H)-tetrazolium-5-carboxanilide (XTT) assay to quantify antifungal activity

包装

1, 5 g in glass bottle

生化/生理作用

2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q₀) interacts with tau protein and aids in the formation of filamentous structure.

基本信息

经验(实验)分子式	C₉H₁₀O₄
分子量	182.17
Beilstein	1640422
EC 号	210-100-8
MDL编号	MFCD00001595
PubChem化学物质编号	24894261

产品性质

质量水平	200
mp	58-60 ℃ (lit.)
储存温度	2-8℃
SMILES string	COC1=C(OC)C(=O)C(C)=CC1=O
InChI	1S/C9H10O4/c1-5-4-6(10)8(12-2)9(13-3)7(5)11/h4H,1-3H3
InChI key	UIXPTCZPFCVOQF-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves