产品说明
一般描述
IgG2c codes for Igh-1b. In mice, IgG2a and IgG2c are arranged in tandem on identical chromosome as two visible loci.
特异性
This antibody reacts to the Fc region of mouse IgG2c. No cross reactivity with mouse IgG1, IgG2a, IgG2b, IgG3, IgM, IgA, IgE, human IgG, or rat IgG.
免疫原
Purified mouse IgG2c whole molecule
生化/生理作用
Mouse IgG2c generate several unique non-bonded interactions between the BC, DE and FG loops than mIgG2b. It connects to FcγRIV (Fc γ receptor IV) with a high affinity in the complex-type glycoform. In mice, IgG2c has unique immune profiles like, response, immune-decoration, because of their difference in protein sequence.
特点和优势
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外形
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.46 |
产品性质
| 质量水平 | 100 |
| 重组 | expressed in HEK 293 cells |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | RM223, monoclonal recombinant monoclonal |
| 形式 | buffered aqueous glycerol solution |
| species reactivity | mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 0.01 μg/mL immunoblotting: 0.5-2 μg/mL (non-reduced only) immunocytochemistry: 0.5-2 μg/mL immunohistochemistry: 0.5-2 μg/mL |
| 同位素/亚型 | IgG |
| NCBI登记号 | 404711 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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