产品说明
一般描述
Myosin is a 500 kD protein that interacts with actin in muscle and in non-muscle cells. It is characterized with two identical heavy chains (200 kD each) and four light chains (15-20 kD each). Myosin molecules consist of two major regions; the tail (rod) and head. These molecules aggregate into filaments through the tail region and interact with actin and ATP through the head region.
特异性
Shows a pattern of staining along stress fibers of cultured human and animal fibroblasts.
免疫原
whole myosin (heavy and light chains) from bovine uterus.
应用
Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit has been used in indirect immunofluorescence labeling.
生化/生理作用
Myosin plays a vital role in neurosensory and cortical function, membrane vesicle trafficking and determinant partitioning. Myosins with actin-stimulated ATPase activity is essential for various cellular movements. Myosins I and V mediates vesicle translocation. Myosin II with a long rod like tail domain, assembles into a bipolar thick filament and facilitate muscle contraction.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00162703 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 200 |
偶联物 | unconjugated |
抗体形式 | whole antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
包含 | 15 mM sodium azide |
species reactivity | animal, human |
technique(s) | indirect immunofluorescence: 1:10 using cultured fibroblasts |
UniProt登记号 | P35579 P35580 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... MYH10(4628), MYH9(4627), MYL9(10398) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich