产品说明
Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe
生化/生理作用
The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. It may be used as a marker for BK production in vivo. It is known that an intact Arg residue in the C-terminus is required for biological activities. BK 1-5 is the minimal peptide that inhibited α-thrombin-induced platelet aggregation and secretion and calcium mobilization. It also prevented α-thrombin from cleaving the thrombin receptor peptide, NATLDPRSFLLR, between arginine and serine. Such antithrombin activities of BK 1-5 may contribute to the cardioprotective nature of kinins.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
基本信息
| 经验(实验)分子式 | C27H40N8O6 |
| 分子量 | 572.66 |
| MDL编号 | MFCD00076260 |
| PubChem化学物质编号 | 24891591 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥97% (HPLC) |
| UniProt登记号 | P01042 |
| 储存温度 | −20℃ |
| SMILES string | NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(O)=O |
| InChI | 1S/C27H40N8O6/c28-18(9-4-12-31-27(29)30)24(38)35-14-6-11-21(35)25(39)34-13-5-10-20(34)23(37)32-16-22(36)33-19(26(40)41)15-17-7-2-1-3-8-17/h1-3,7-8,18-21H,4-6,9-16,28H2,(H,32,37)(H,33,36)(H,40,41)(H4,29,30,31) |
| InChI key | USSUMSBPLJWFSZ-UHFFFAOYSA-N |
| Gene Information | human ... KNG1 (includes EG:3827)(3827) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
