4′-O-甲基-8-γ，γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷

产品名称：

489-32-7
Icariin
4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside
淫羊藿甙
4′-O-甲基-8-γ，γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷

产品介绍：

产品说明

一般描述

Icariin is a prenylated flavonol and the major bioactive compound found in Epimedium herb.

应用

Icariin has been used:

in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats
to test its analgesic effects on lower back pain (LBP) in rats
as a potential treatment in osteoporosis condition in rats
to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes
as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells

包装

100 mg in poly bottle
1 g in poly bottle

生化/生理作用

Icariin is a potent neuroprotective agent in neurodegenerative disorders and other disorders affecting the nervous system. It elicits anti-aging properties in unfertilized oocytes against age-related damage. Icariin exerts anti-inflammatory and antifibrotic properties aiding protection in chronic kidney disease (CKD)-associated renal fibrosis in mouse model. It also serves as an excellent antidiabetic and anti-atherosclerotic agent. Icariin is an excellent anti-cancer agent.
来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成，并表现出抗氧化活性。

基本信息

经验(实验)分子式	C₃₃H₄₀O₁₅
分子量	676.66
MDL编号	MFCD00210516
PubChem化学物质编号	329815347
NACRES	NA.25

产品性质

质量水平	100
测定	≥94% (HPLC)
颜色	light yellow to yellow
溶解性	DMSO: 50 mg/mL, clear, colorless to dark yellow
储存温度	room temp
SMILES string	COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI	1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI key	TZJALUIVHRYQQB-XLRXWWTNSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable