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位置:首页 > 品牌 > Sigma-Aldrich > 4′-O-甲基-8-γ,γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷

Icariin

4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

品牌
Sigma-Aldrich
CAS
489-32-7
货号
I1286
规格纯度
≥94% (HPLC)
参考价格
1777.23 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
489-32-7
Icariin
4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside
淫羊藿甙
4′-O-甲基-8-γ,γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷
产品介绍:

产品说明

一般描述

Icariin is a prenylated flavonol and the major bioactive compound found in Epimedium herb.

应用

Icariin has been used:

  • in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats
  • to test its analgesic effects on lower back pain (LBP) in rats
  • as a potential treatment in osteoporosis condition in rats
  • to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes
  • as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells

包装

100 mg in poly bottle
1 g in poly bottle

生化/生理作用

Icariin is a potent neuroprotective agent in neurodegenerative disorders and other disorders affecting the nervous system. It elicits anti-aging properties in unfertilized oocytes against age-related damage. Icariin exerts anti-inflammatory and antifibrotic properties aiding protection in chronic kidney disease (CKD)-associated renal fibrosis in mouse model. It also serves as an excellent antidiabetic and anti-atherosclerotic agent. Icariin is an excellent anti-cancer agent.
来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成,并表现出抗氧化活性。

基本信息

经验(实验)分子式C33H40O15
分子量676.66
MDL编号MFCD00210516
PubChem化学物质编号329815347
NACRESNA.25

产品性质

质量水平100
测定≥94% (HPLC)
颜色light yellow to yellow
溶解性DMSO: 50 mg/mL, clear, colorless to dark yellow
储存温度room temp
SMILES stringCOc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI keyTZJALUIVHRYQQB-XLRXWWTNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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