RK-682

产品名称：

150627-37-5
RK-682
(R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid
(R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone

产品介绍：

产品说明

应用

RK-682 has been used:

as a positive control in high-performance liquid chromatography (HPLC)
as a reference compound in high-performance liqiud chromatography (HPLC)
as a pan-protein tyrosine phosphatase non-receptor type (PTPN) inhibitor to study its effects on the activated lymphocytes

包装

1 mg in glass bottle
200 μg in glass bottle

生化/生理作用

Specific and noncompetitive inhibitor of protein tyrosine phosphatase.
RK-682 is a specific and noncompetitive inhibitor of protein tyrosine phosphatase; It inhibited dephosphorylation activity of CD45 and VHR with IC50 54 and 2.0 microM and 4.5 microM against PTP1B.

特点和优势

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₂₁H₃₆O₅
分子量	368.51
MDL编号	MFCD20488046
PubChem化学物质编号	329824012
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to tan
溶解性	DMSO, heptane and xylene: ≥8 mg/mL
储存温度	−20℃
SMILES string	CCCCCCCCCCCCCCCC(=O)C1=C(O)[C@@H](CO)OC1=O
InChI	1S/C21H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(23)19-20(24)18(16-22)26-21(19)25/h18,22,24H,2-16H2,1H3/t18-/m1/s1
InChI key	KZTSLHQKWLYYAC-GOSISDBHSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable