W146

品牌

Avanti

CAS

909725-62-8

货号

857390P

包装型号

规格纯度

(R)-3-Amino-(3-hexylphenylamino)-4-oxobutylphosphonic acid (TFA salt), powder

参考价格

2854.09 元 *本价格含增值税费

促销

数量

产品名称：

909725-62-8
W146
S1P1 Antagonist

产品介绍：

产品说明

一般描述

W146 is a sphingosine-1-phosphate 1 (S1P1) selective antagonist.
Compound 2a is a selective antagonist for human S1P1 (hS1P1) receptor activation by the physiological agonist S1P.

应用

W146 has been used:

to verify the mode of action of sphingosine-1-phosphate (S1P) in human bone marrow derived mesenchymal stem cells (hMSCs ) and primary human hepatogenic profibrotic cells (hHPCs)
to study oxidative stress and drug treatment in granulosa cells
to evaluate its effects on transendothelial electrical resistance (TEER)

生化/生理作用

W146 acts as an orthosteric antagonist. It is linked to blood lymphopenia and lung edema in mice.

包装

5 mL Amber Glass Screw Cap Vial (857390P-10mg)
5 mL Amber Glass Screw Cap Vial (857390P-1mg)

基本信息

经验(实验)分子式	C₁₈H₂₈F₃N₂O₆P
分子量	456.39
NACRES	NA.25

产品性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 1 mg (857390P-1mg) pkg of 1 × 10 mg (857390P-10mg)
manufacturer/tradename	Avanti Polar Lipids 857390P
运输	dry ice
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	No data available
闪点(C)	No data available