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Anti-τ (Tau) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
T6402
规格纯度
whole antiserum
参考价格
5549.05 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-τ (Tau) antibody produced in rabbit
产品介绍:

产品说明

一般描述

Tau (τ), also known as microtubule associated protein tau (MAPT) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons. Tau is a heat stable microtubule associated protein (MAP) with a molecular weight of 55- 65 kDa.
Tau (τ), also known as MAPT (microtubule associated protein tau) is encoded by the gene mapped on human chromosome 17q21.3. It is highly expressed in neurons but is most prominent in axons.

特异性

The antibody shows wide species reactivity. Anti-τ does not react with MAP1, MAP2 or tubulin. the antibody reacts with τ, one of the two major classes of heat stable microtubule-associated proteins (MAPs).

免疫原

τ proteins from chicken embryo brain microtubules.

应用

Anti-τ (Tau) antibody produced in rabbit has been used as a primary antibody in western blotting.

生化/生理作用

Removal of Tau (τ) results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). Tau helps in the assembly and maintenance of microtubule structure.
Variation in the MAPT gene encoding tau protein results in frontotemporal dementia. Tau protein acts as a substrate for many kinases.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00164745
NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式whole antiserum
antibody product typeprimary antibodies
克隆polyclonal
包含15 mM sodium azide
species reactivityrat, chicken, mouse
technique(s)western blot: 1:100 using rat or mouse brain tissue extract
UniProt登记号P19332
运输dry ice
储存温度−20℃
Gene Informationhuman ... MAPT(4137)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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