Cinoxacin

产品名称：

28657-80-9
Cinoxacin
1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid

产品介绍：

产品说明

一般描述

Chemical structure: quinolone

应用

Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes.

生化/生理作用

Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C8645.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Keep container tightly closed in a dry and well-ventilated place.

基本信息

经验(实验)分子式	C₁₂H₁₀N₂O₅
分子量	262.22
EC 号	249-133-8
MDL编号	MFCD00056776
PubChem化学物质编号	24278343
NACRES	NA.85

产品性质

质量水平	200
形式	powder or crystals
作用机制	DNA synthesis \| interferes enzyme \| inhibits
抗生素抗菌谱	Gram-negative bacteria
SMILES string	CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12
InChI	1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)
InChI key	VDUWPHTZYNWKRN-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)