七(2,3,6-三-O-甲基)-β-环糊精

产品名称：

55216-11-0
Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin
TM-β-CD
TRIMEB
2,3,6-Tri-O-methyl-β-cyclodextrin
TM‐β‐CyD
Trimethyl-β-cyclodextrin
七(2,3,6-三-O-甲基)-β-环糊精
三甲基-β-环式糊精
2,3,6-三-O-甲基-β-环糊精

产品介绍：

产品说明

一般描述

Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin is a β-cyclodextrin derivative that finds potential use in pharmaceutical, food and cosmetic applications. Its attractive features include: the non-polar cavity desirable for its use as a molecular host for a wide range of molecules and its affinity for organic compounds in solution as well as crystalline phases.

应用

Heptakis(2,3,6-tri-O-methyl)-β-cyclodextrin may be used:

To investigate the crystal structure of its complexes with m-iodophenol, 4-biphenylacetic acid and (R)- and (S)-flurbiprofen by X-ray analysis.
To study the candidature of its complex with vitamin A for potential application as a drug delivery system for ophthalmic applications by high sensitivity fluorescence spectrometry and high pressure liquid chromatography (HPLC).
In the determination of analyte composition in commercial samples by HPLC coupled to mass spectrometry (MS).

用于对映体拆分的液相色谱的手性添加剂。通过毛细管电泳对碱性药物的手性分离。

基本信息

经验(实验)分子式	C₆₃H₁₁₂O₃₅
分子量	1429.54
Beilstein	78748
MDL编号	MFCD00010728
PubChem化学物质编号	329757734
NACRES	NA.22

产品性质

质量水平	100
测定	≥98.0% (TLC) ≥98.0%
旋光性	[α]25/D +157±4°, c = 1% in H₂O
mp	170-178 ℃ (lit.)
溶解性	H₂O: 50 mg/mL, slightly turbid, colorless
储存温度	2-8℃
SMILES string	COC[C@H]1O[C@@H]2O[C@@H]3[C@@H](COC)O[C@H](O[C@@H]4[C@@H](COC)O[C@H](O[C@@H]5[C@@H](COC)O[C@H](O[C@@H]6[C@@H](COC)O[C@H](O[C@@H]7[C@@H](COC)O[C@H](O[C@@H]8[C@@H](COC)O[C@H](O[C@H]1[C@H](OC)[C@H]2OC)[C@H](OC)[C@H]8OC)[C@H](OC)[C@H]7OC)[C@H](OC)[C@H]6OC)[C@H](OC)[C@H]5OC)[C@H](OC)[C@H]4OC)[C@H](OC)[C@H]3OC
InChI	1S/C63H112O35/c1-64-22-29-36-43(71-8)50(78-15)57(85-29)93-37-30(23-65-2)87-59(52(80-17)44(37)72-9)95-39-32(25-67-4)89-61(54(82-19)46(39)74-11)97-41-34(27-69-6)91-63(56(84-21)48(41)76-13)98-42-35(28-70-7)90-62(55(83-20)49(42)77-14)96-40-33(26-68-5)88-60(53(81-18)47(40)75-12)94-38-31(24-66-3)86-58(92-36)51(79-16)45(38)73-10/h29-63H,22-28H2,1-21H3/t29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43+,44+,45+,46+,47+,48+,49+,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m1/s1
InChI key	DSDAICPXUXPBCC-MWDJDSKUSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)