M871 trifluoroacetate

产品名称：

M871 trifluoroacetate
WTLNSAGYLLGPEHPPPALALA-NH2, TFA salt
M 871, TFA salt
Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide, TFA salt
M-871, TFA salt
Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Glu-His-Pro-Pro-Pro-Ala-Leu-Alal-Leu-Ala-NH2, TFA salt

产品介绍：

产品说明

生化/生理作用

M871 is a type 2-selective galanin receptor antagonist (GalR2/GalR1 K_i = 13.1/410 nM by competitive binding against 0.1 nM porcine galanin using membranes from CHO expressing respective human receptors; GalR2/GalR1 K_i = 2.5/1.1 nM in case of rat galanin) that potently blocks 10 nM rat galanin-induced inositol phosphate production in human GalR2-expressing CHO cells (by 100% with 0.1, 1 or 10 nM M871). M871 is widely employed in cultures (0.1 nM-2.5 μM) and in mice and rats in vivo via ip., brain region- or other site-specific injections.

基本信息

经验(实验)分子式	C₁₀₈H₁₆₃N₂₇O₂₈ · xC₂HF₃O₂
分子量	2287.61 (free base basis)

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	lyophilized powder
颜色	white to off-white
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable