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Mca-APK(Dnp)-OH trifluoroacetate

品牌
Sigma-Aldrich
货号
SML2948
规格纯度
≥97% (HPLC)
参考价格
1438.81 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Mca-APK(Dnp)-OH trifluoroacetate
Mca-APK(Dnp) TFA salt (Mca = 7-Methoxycoumarin-4-yl; Dnp = 2,4-dinitrophenyl)
Mca-Ala-Pro-Lys(Dnp)-OH TFA salt
Mca-Ala-Pro-Lys(Dnp) TFA salt
产品介绍:

产品说明

生化/生理作用

Mca-APK(Dnp)-OH is a widely used fluorescent substrate for angiotensin-converting enzyme 2 (ACE2 cleaves between P & K). Proteolytic cleavage separates 7-methoxycoumarin-4-acetyl (Mca) from the fluorescence-quenching group 2,4-dinitrophenyl (Dnp), resulting in increased Mca fluorescence (Ex: 320-328 nm, Em: 405-420 nm). The fluorescence increase over background upon Mca-APK(Dnp) cleavage is more than 14-fold higher than that of Mca-YVADAPK(Dnp), while only Mca-YVADAPK(Dnp), but not Mca-APK(Dnp), can also be used for assessing caspase-1 (ICE) activity.

基本信息

经验(实验)分子式C32H36N6O12
分子量696.66

产品性质

质量水平100
测定≥97% (HPLC)
形式film or powder
颜色 white to dark beige
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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