N- <i>cis</i>-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na

产品名称：

BQ-788, Sodium Salt-CAS-Calbiochem
N- cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na

产品介绍：

产品说明

一般描述

A highly selective and competitive ETB receptor antagonist (IC₅₀ = 1.2 nM).
Highly selective ET_B-receptor antagonist (IC₅₀ = 1.2 nM).

生化/生理作用

Primary Target
ETB-receptor antagonist
Target IC₅₀: 1.2 nM as ETB-receptor antagonist
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Standard Handling (A)

重悬

Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.

其他说明

Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₃₄H₅₀N₅NaO₇
分子量	663.78

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	lyophilized solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated
颜色	white to off-white
溶解性	0.01% NH₄OH: 1 mg/mL DMSO: 2 mg/mL methanol: water (3:1): 2 mg/mL
运输	ambient
储存温度	−20℃

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable