产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. For further information and support please go to the website of the issuing pharmacopoeia. Calcitriol is a biologically active metabolite of vitamin D, formed via hydroxylation of calcidiol in the kidney.
生化/生理作用
在钙的吸收和沉积中维生素D3的生物活性形式。 1α,25-二羟基维生素D3对细胞分化和增殖具有广泛的作用,并可调节免疫应答和中枢神经系统功能。最近的研究表明,1α,25-二羟基维生素D3可作为抵抗包括前列腺癌和结肠癌在内数种恶性肿瘤的化学预防剂,并显示出了与其他抗癌化合物的协同作用。
包装
Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
经验(实验)分子式 | C27H44O3 |
分子量 | 416.64 |
Beilstein | 7559394 |
MDL编号 | MFCD00867079 |
PubChem化学物质编号 | 329774770 |
NACRES | NA.24 |
产品性质
生物来源 | sheep wool (grease) |
等级 | pharmaceutical primary standard |
agency | EP |
形式 | solid |
manufacturer/tradename | EDQM |
technique(s) | gas chromatography (GC): suitable liquid chromatography (LC): suitable |
application(s) | pharmaceutical (small molecule) |
格式 | neat |
储存温度 | −20℃ |
SMILES string | [H][C@@]1(CC[C@@]2([H])C(\CCC[C@]12C)=C\C=C3\C[C@@H](O)C[C@H](O)C3=C)[C@H](C)CCCC(C)(C)O |
InChI | 1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 |
InChI key | GMRQFYUYWCNGIN-NKMMMXOESA-N |
Gene Information | human ... VDR(7421) |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H300 + H310 + H330 - H372 |
预防措施声明 | P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
危险分类 | Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - STOT RE 1 |
储存分类代码 | 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich