产品说明
一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
生化/生理作用
生物活性最强的前列腺素。PGE2 可诱导宫颈成熟和分娩，介导缓激肽诱导的血管舒张，调节腺苷酸环化酶。 过表达环加氧酶2的肿瘤细胞具有更强的侵袭性、血管生成能力和细胞凋亡抵抗性，这可能是由于PGE2诱导的血管生成因子表达以及抗凋亡蛋白survivin的稳定化。PGE2 对免疫系统具有混合效应。它在体外抑制T细胞活化，表明它是一种免疫抑制剂。然而，在体内，它影响Th17亚群的扩增和T辅助细胞Th1亚群的分化，表明它是一种免疫激活剂。
包装
Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
注意
Please find SDS provided by EDQM here..
其他说明
Sales restrictions may apply.
基本信息
| 经验(实验)分子式 | C20H32O5 |
| 分子量 | 352.47 |
| Beilstein | 4709356 |
| MDL编号 | MFCD00077861 |
| PubChem化学物质编号 | 329798733 |
| NACRES | NA.24 |
产品性质
| 等级 | pharmaceutical primary standard |
| manufacturer/tradename | EDQM |
| application(s) | pharmaceutical (small molecule) |
| 格式 | neat |
| SMILES string | O[C@@H]1CC([C@H](C/C=C\CCCC(O)=O)[C@H]1/C=C/[C@@H](O)CCCCC)=O |
| InChI | 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 |
| InChI key | XEYBRNLFEZDVAW-ARSRFYASSA-N |
| Gene Information | human ... PTGER1(5731), PTGER2(5732), PTGER3(5733), PTGER4(5734) |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H360 |
| 预防措施声明 | P201 - P301 + P312 + P330 - P308 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Repr. 1B |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
