产品说明
一般描述
An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).
An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.
包装
1 kg in Glass bottle
25, 100 g in Glass bottle
警告
Toxicity: Harmful (C)
其他说明
Pai, R., et al. 2004. Mol. Biol. Cell15 2156.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C24H39NaO4 |
分子量 | 414.55 |
Beilstein | 3581950 |
MDL编号 | MFCD00064139 |
产品性质
质量水平 | 100 |
测定 | ≥96% (TLC) |
形式 | powder |
分子量 | micellar avg mol wt 1200-5000 micellar wt 1700-4200 |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated (hygroscopic) |
聚集数 | 3-12 4 - 10 |
颜色 | white to off-white |
pKa | 6.2 |
CMC | 2-6 mM (20-25℃) 4 - 8 mM |
溶解性 | H2O: 2%, clear, colorless |
痕量阳离子 | heavy metals: ≤20.0 ppm |
HLB | 16 |
运输 | ambient |
储存温度 | 15-25℃ |
SMILES string | [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2 |
InChI | 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1 |
InChI key | FHHPUSMSKHSNKW-SMOYURAASA-M |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H412 |
预防措施声明 | P264 - P270 - P273 - P301 + P312 - P501 |
危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 3 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich