产品说明
应用
3,5-Dinitrocatechol (3,5-DNC) has been used in the preparation of the molybdenum (VI)-(3,5-DNC) complex. It has also been used as a catechol-O-methyltransferase (COMT) inhibitor and as a positive control for screening human COMT inhibition.
Chelating reagent used in a sensitive (μM) assay for vanadium.
包装
250 mg in poly bottle
50 mg in glass insert
生化/生理作用
Selective inhibitor of catechol O-methyl transferase (COMT); penetrates the blood brain barrier and is useful both orally and parenteraly in experiments where inhibition of COMT in the central nervous system is required.
质量
Solutions may be stored for several days at 4 ℃.
注意
Photosensitive
基本信息
| 经验(实验)分子式 | C6H4N2O6 |
| 分子量 | 200.11 |
| MDL编号 | MFCD00069263 |
| PubChem化学物质编号 | 24278158 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | yellow |
| mp | 168-170 ℃ |
| 溶解性 | H2O: slightly soluble 0.17 mg/mL 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.8 mg/mL 0.1 M HCl: slightly soluble DMSO: soluble aqueous buffer pH > 5: soluble ethanol: soluble |
| 储存温度 | 2-8℃ |
| SMILES string | Oc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O |
| InChI | 1S/C6H4N2O6/c9-5-2-3(7(11)12)1-4(6(5)10)8(13)14/h1-2,9-10H |
| InChI key | VDCDWNDTNSWDFJ-UHFFFAOYSA-N |
| Gene Information | human ... COMT(1312) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
