产品说明
应用
Adenosine 5′-[β-thio]diphosphate trilithium salt has been used to induce neuropathic pain in rats to study the effect of dorsal horn cannabinoid CB2 receptor activation on the expression of P2Y12 and P2Y13 (purinoceptors) receptors.
Adenosine 5′-[β-thio]diphosphate is a substrate and inhibitor for AMP dependent enzyme systems. Adenosine 5′-[β-thio]diphosphate has been used to explore the myenteric control mechanisms of human esophageal motility and the effect of nitrergic and nonnitrergic neurotransmitters.
生化/生理作用
P2Y 受体激动剂。
特点和优势
This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
其他说明
Non-hydrolyzable ADP analog
底物
Substrate and inhibitor for AMP dependent enzyme systems.
基本信息
| 经验(实验)分子式 | C10H12Li3N5O9P2S |
| 分子量 | 461.07 |
| MDL编号 | MFCD00077314 |
| eCl@ss | 32160414 |
| PubChem化学物质编号 | 24891307 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥80% (HPLC) |
| 形式 | powder |
| 储存温度 | −20℃ |
| SMILES string | [Li+].[Li+].[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O |
| InChI | 1S/C10H15N5O9P2S.3Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(23-10)1-22-25(18,19)24-26(20,21)27;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H2,11,12,13)(H2,20,21,27);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1 |
| InChI key | CPKFUAYUUSSFFZ-MSQVLRTGSA-K |
安全信息
| 象形图 |   |
| 警示用语： | Warning |
| 危险声明 | H302 - H371 |
| 预防措施声明 | P301 + P312 + P330 - P308 + P311 |
| 危险分类 | Acute Tox. 4 Oral - STOT SE 2 |
| 靶器官 | Eyes |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
