产品说明
应用
Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
包装
100 g in poly bottle
基本信息
| 线性分子式 | C5H3N2O4K |
| 分子量 | 194.19 |
| EC 号 | 246-341-0 |
| MDL编号 | MFCD00039118 |
| PubChem化学物质编号 | 24897970 |
| NACRES | NA.51 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% |
| 形式 | powder |
| 溶解性 | 1 M NaOH: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| SMILES string | [K+].[O-]C(=O)C1=CC(=O)NC(=O)N1 |
| InChI | 1S/C5H4N2O4.K/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);/q;+1/p-1 |
| InChI key | DHBUISJCVRMTAZ-UHFFFAOYSA-M |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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