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ApoJ/Clusterin human

品牌
Sigma-Aldrich
货号
SRP6548
规格纯度
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
参考价格
3749.34 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
ApoJ/Clusterin human
Clusterin Apolipoprotein J
SGP2
TRPM2
SGP-2
CLI
KUB1
AAG4
MGC24903
产品介绍:

产品说明

一般描述

Native Apolipoprotein J (ApoJ), also named Clusterin, is a heavily glycosylated, 75-80 kDa disulfide-linked heterodimeric protein. Despite being cloned since 1989, no genuine function has been attributed to ApoJ so far. The protein has been reportedly implicated in several diverse physiological processes such as sperm maturation, lipid transportation, complement inhibition, tissue remodeling, membrane recycling, cell-cell and cell-substratum interactions, stabilization of stressed proteins in a folding-competent state and promotion or inhibition of apoptosis. ApoJ gene is differentially regulated by cytokines, growth factors and stress-inducing agents. Clusterin is up- or down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.

外形

Lyophilized from 2 mg/mL solution of ApoJ in 25 mM Na2HPO4 and 100 mM NaCl (pH 7.5).

重悬

Reconstitute in dH2O to a working concentration of 0.5 mg/mL and let the lyophilized pellet dissolve completely.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥90% (SDS-PAGE)
形式lyophilized
分子量 51.1 kDa (23-449 aa with a C-terminal His-tag.)
包装pkg of 1 mg
pkg of 10 μg
pkg of 50 μg
UniProt登记号P10909
运输wet ice
储存温度−20℃
Gene Informationhuman ... CLU(1191)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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