产品说明
一般描述
BrdT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence. The bromodomain is found in proteins that regulate transcription. BrdT drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids. It may play a role in the transcriptional regulation of spermatogenesis. It also seems to have a structural ATP-independent role in the reorganization of acetylated chromatin. Therecombinant protein includes Bromo 1 domain (257-382 aa) with N-terminal His-tag.
外形
rh-BrdT is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 14.9 kDa (126 aa, 257-382 aa + NT His Tag) |
| 包装 | pkg of 1 mg pkg of 100 μg pkg of 20 μg |
| NCBI登记号 | NM_207189 |
| UniProt登记号 | Q58F21 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... BRDT(676) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
