产品说明
一般描述
Sensitive fluorogenic substrate for the quantitative determination of human leukocyte (Km = 140 µM; Kcat/Km = 120,000 s-1 M-1) and porcine pancreatic elastase. Not hydrolyzed by cathepsin G. Excitation max.: ~380 nm; emission max.: ~460 nm.
Sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 µM; kcat/Km = 120,000 M-1 s-1). Not hydrolysed by cathepsin G.
包装
25 mg in Plastic ampoule
生化/生理作用
Km = 140 µM; kcat/Km = 120,000 M⁻¹ s⁻¹as substrates for human leukocyte and porcine pancreatic elastase
Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase
警告
Toxicity: Standard Handling (A)
序列
MeOSuc-Ala-Ala-Pro-Val-AMC
重悬
Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 2 months at -20°C.
其他说明
Barrett, A.J. 1981. Methods Enzymol. 80, 581.
Castillo, M.J., et al. 1979. Anal. Biochem.99, 53.
Nakajima, K., et al. 1979. J. Biol. Chem.254, 4027.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C31H41N5O9 |
| 分子量 | 627.69 |
| MDL编号 | MFCD00077135 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥95% (HPLC) ≥95% (TLC) |
| 形式 | lyophilized solid powder |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated protect from light |
| 颜色 | white to off-white |
| 溶解性 | ethanol: 1 mg/mL DMF: 5 mg/mL DMSO: 5 mg/mL |
| 荧光 | λex 360-380 nm λem 430-460 nm |
| 运输 | ambient |
| 储存温度 | −20℃ |
| InChI | 1S/C31H41N5O9/c1-16(2)27(34-20-9-10-21-17(3)14-26(39)45-23(21)15-20)30(42)35-29(41)22-8-7-13-36(22)31(43)19(5)33-28(40)18(4)32-24(37)11-12-25(38)44-6/h9-10,14-16,18-19,22,27,34H,7-8,11-13H2,1-6H3,(H,32,37)(H,33,40)(H,35,41,42)/t18-,19-,22-,27-/m0/s1 |
| InChI key | NHMQNKPYBPDCAY-NFHWZJRKSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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