N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide

产品名称：

189950-66-1
N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide
Ac-DEVD-pNA

产品介绍：

产品说明

Amino Acid Sequence

NAc-Asp-Glu-Val-Asp-pNA

应用

N-Acetyl-Asp-Glu-Val-Asp p-nitroanilide has been used as a chromogenic substrates for determining caspase-3 and caspase-8 activities in liver tissue homogenates and caspase 3 activity in aortic vascular smooth muscle cells and neuroblastoma cell lines.

包装

5 mg in glass bottle

生化/生理作用

Colorimetric substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.

基本信息

经验(实验)分子式	C₂₆H₃₄N₆O₁₃
分子量	638.58
MDL编号	MFCD00792707
PubChem化学物质编号	24890668
NACRES	NA.32

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white
储存温度	−20℃
SMILES string	CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI	1S/C26H34N6O13/c1-12(2)22(26(43)30-18(11-21(38)39)24(41)28-14-4-6-15(7-5-14)32(44)45)31-23(40)16(8-9-19(34)35)29-25(42)17(10-20(36)37)27-13(3)33/h4-7,12,16-18,22H,8-11H2,1-3H3,(H,27,33)(H,28,41)(H,29,42)(H,30,43)(H,31,40)(H,34,35)(H,36,37)(H,38,39)/t16-,17-,18-,22-/m0/s1
InChI key	GGXRLUDNGFFUKI-ORGXJRBJSA-N
Gene Information	human ... CASP3(836)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)