产品说明
应用
Sparfoxacin is used to study antimicrobial activity against Mycobacteria and respiratory tract infections .
生化/生理作用
Sparfloxacin fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. It inhibits bacterial DNA gyrase-dependent processes such as DNA polymerization, ATP-dependent-DNA supercoiling, and chromosome fragmentation.
包装
1g, 10g
其他说明
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids
基本信息
经验(实验)分子式 | C19H22F2N4O3 |
分子量 | 392.40 |
Beilstein | 9170271 |
MDL编号 | MFCD00869619 |
PubChem化学物质编号 | 57651613 |
NACRES | NA.85 |
产品性质
质量水平 | 200 |
生物来源 | synthetic |
测定 | ≥98.0% (HPLC) |
形式 | powder |
颜色 | white to light yellow |
作用机制 | enzyme | inhibits |
抗生素抗菌谱 | Gram-negative bacteria Gram-positive bacteria mycobacteria mycoplasma |
SMILES string | C[C@H]1CN(C[C@@H](C)N1)c2c(F)c(N)c3C(=O)C(=CN(C4CC4)c3c2F)C(O)=O |
InChI | 1S/C19H22F2N4O3/c1-8-5-24(6-9(2)23-8)17-13(20)15(22)12-16(14(17)21)25(10-3-4-10)7-11(18(12)26)19(27)28/h7-10,23H,3-6,22H2,1-2H3,(H,27,28)/t8-,9+ |
InChI key | DZZWHBIBMUVIIW-DTORHVGOSA-N |
Gene Information | human ... KCNH1(3756), TOP2A(7153) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H315 - H319 - H335 |
预防措施声明 | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich