胞苷-5′-单磷氮乙酰神经氨酸钠盐

产品名称：

3063-71-6
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt
CMP-NANA
CMP-Neu5Ac
CMP-NAN
CMP-Sialic acid
胞苷-5′-单磷氮乙酰神经氨酸钠盐
CMP-唾液酸

产品介绍：

产品说明

一般描述

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is a sugar-nucleotide produced by CMP-Neu5Ac synthetase from CTP and Neu5Ac.

应用

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used:

as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts,
As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay,
in in-vitro sialyltransferase assay

包装

25 mg in poly bottle
1, 5 mg in glass bottle

生化/生理作用

Cytosine 5′-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac) is used as a substrate for Golgi sialyltransferases to form sialic acid and its conjugates.
胞苷-5′-单磷酸酯-N-乙酰基神经氨酸(CMP-唾液酸)是唾液酸转移酶的底物。主要用于多糖的酶促唾液酸化。

制备说明

通过Schauer, R.等人Hoppe Seyler′s Z. Physiol. Chem., 353, 883 (1972)的方法酶促制备。
CMP-NAN是非常酸不稳定的。

基本信息

线性分子式	C₂₀H₃₁N₄O₁₆P
分子量	636.43
Beilstein	4224251
MDL编号	MFCD00151579
PubChem化学物质编号	24893038
NACRES	NA.51

产品性质

质量水平	200
测定	≥85% (HPLC)
储存温度	−20℃
SMILES string	[Na+].CC(=O)N[C@@H]1[C@@H](O)C[C@@](O[C@@H]1[C@H](O)[C@H](O)CO)(OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(N)=NC3=O)C(O)=O
InChI	1S/C20H31N4O16P.Na/c1-7(26)22-12-8(27)4-20(18(32)33,39-16(12)13(29)9(28)5-25)40-41(35,36)37-6-10-14(30)15(31)17(38-10)24-3-2-11(21)23-19(24)34;/h2-3,8-10,12-17,25,27-31H,4-6H2,1H3,(H,22,26)(H,32,33)(H,35,36)(H2,21,23,34);/q;+1/p-1/t8-,9+,10+,12+,13+,14+,15+,16?,17+,20+;/m0./s1
InChI key	VFRHSOGUONIUOR-CTFMUGKASA-M

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt

胞苷-5′-单磷氮乙酰神经氨酸 钠盐

胞苷-5′-单磷氮乙酰神经氨酸钠盐